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The Brain: Let's Think

Neurotransmitters:

  • Glutamate

  • Aminobutyric

  • Serotonin

  • Histamine

  • Acetylcholine

  • Taurine

  • Glycine

  • Norepinephrine

  • Dopamine

  • Adrenaline


Fun Fact:

The brain is an organ, not a muscle.


What are neurotransmitters:

Neurotransmitters are endogenous chemicals (the body's chemical messengers) that allow neurons to communicate with parts of the body. They carry, boost, and balance the body via a process called chemical synaptic transmission. Neurotransmitters help the body function and are essential for shaping everyday life. At its core, the intricate human system is governed by neurotransmitters, which act as messengers within the central nervous system (CNS), influencing a myriad of bodily functions such as mood, muscle movement, and heart rate. These transmitters play a vital role in amplifying, transmitting, and converting signals within cells, facilitating the seamless transmission of information throughout the system to function; including awareness, movement, thinking, and speech.


GABA and serotonin are examples of inhibitory neurotransmitters. They are responsible for the relaxation of the nervous system and the feeling of calmness and well-being. When serotonin levels are low you may feel depressed or lack of motivation. The ebb and flow of estrogen levels throughout a woman's cycle can impact neurotransmitters such as serotonin, dopamine, and norepinephrine, for individuals with estrogen dominance, mood swings and feelings of melancholy may occur more frequently. Estrogen plays a crucial role in cognitive functions such as memory, focus, and quick thinking. Women often complain of brain fog and fatigue at some point throughout their cycle and this could be why. Menopause, often misunderstood, is essentially a hormone imbalance and doesn't need to be an unpleasant experience. By focusing on strategies that support the aging process and hormone changes, "The Change" can effectively be managed, making it a more positive experience. Check out the blog post 'Estrogen Toxicity: Common not normal' for more insights.


A branch of the immune system called macrophages are a type of white blood cell that are important in your immunity. They are responsible for engulfing and digesting cellular debris, foreign substances, microbes, and cancer cells through a process called phagocytosis. Macrophages also release signaling molecules, known as cytokines to regulate the immune response and inflammation. Microglia, on the other hand, are a type of glial cell found in the central nervous system (CNS). They function as the primary immune cells in the brain and spinal cord, serving roles similar to those of macrophages in the rest of the body. Microglia actively survey the brain for abnormalities and respond to injury, infection, or neurodegenerative diseases by phagocytosing invading microorganisms and cellular debris.


They also release signaling molecules and interact with other cells in the nervous system to modulate the immune response and maintain brain homeostasis. Both macrophages and microglia play essential roles in the body's immune defense, tissue repair, and maintenance of overall homeostasis. Their activities are critical for overall health and protection against infections and diseases. Histamine is a compound involved in the immune response and acts as a signaling molecule in various bodily systems. In response to allergens or irritants, histamine triggers the inflammation and other physiological responses characteristic of allergic reactions, such as nasal congestion, itching, and hives. It serves as a warning signal alerting the body to potentially harmful substances. These neurotransmitters and hormones are integral to the body's response to various stimuli and play important roles in regulating both physical and emotional processes.


Adrenaline, also known as epinephrine, is a hormone and neurotransmitter released in response to stress or fear. It triggers the body's "fight or flight" response, increasing heart rate, dilating airways, and providing a surge of energy to deal with a perceived threat. Chronic stress and constant activation of the fight or flight response can lead to adrenal fatigue, a condition characterized by exhaustion and high levels of the stress hormone cortisol. Serotonin is a neurotransmitter often referred to as the "happy chemical." It plays an important role in regulating mood, happiness, and anxiety. Studies have suggested that activities like hugging and kissing can increase serotonin levels, contributing to feelings of joy and love. Additionally, maintaining healthy serotonin levels has been linked to improved overall well-being.


Fun Fact:

Studies have shown when you hug or kiss for a minimum of 6 seconds at a time you increase your serotonin levels and longevity. It takes roughly 6 seconds for the synaptic transmission to recognize and release the chemical that creates the feeling of love and joy.


Myelin is another major component of the brain and nervous system. Myelin sheaths are elements that serve as a protective fatty membrane enveloping the brain and nerve fibers throughout the body. It acts as an electrical conductor, enabling swift and smooth transmission of chemical signals between nerve cells while also safeguarding the strength of these signals as they traverse the brain. Damage to myelin can disrupt nerve impulses, leading to neurological symptoms like impaired motor functions, tremors, vision problems, and changes in bowel or bladder functions. Fortunately, myelin has the potential to be repaired or replaced. Oligodendrocytes and Schwann cells are responsible for the repair process. Recent studies have highlighted the role of vitamin D as a vital receptor for promoting the differentiation of oligodendrocyte progenitor cells, thereby bolstering myelin sheath regeneration. With proper steps, myelin can take as little as 3 months to repair.


Did You Know:

A common brain disease that causes demyelination is MS (multiple sclerosis). It is a disease of the CNS and essentially diminishes myelin sheaths. It affects about 1 million people in the US and affects more women than men.


It is important to note the significance of myelin in facilitating communication between neurotransmitters throughout the body. The intricate network of 100 billion functional nerve cells enables the transmission and reception of messages from all parts of the body. Without the proper function of these cells, no part of the body would operate as intended. Being that myelin is a conductor of energy it's imperative to maintain a healthy diet that includes omegas and amino acids to support them.


Note:

Recovery offers comprehensive support to the body by serving as an intestinal microbiome reset, structural fat pad restorer, and a vital source of lipids essential for cell function.

Did you know the liver plays a role in neurotransmitters?

The connection between the liver and neurotransmitters lies in the metabolic processes that occur in the liver. The liver's purpose in the body is underrated across the board. In this situation, the liver's role is the metabolism of neurotransmitters and is responsible for the breakdown and detoxification of various substances. For instance, the liver metabolizes and detoxifies neurotransmitters such as serotonin, dopamine, and norepinephrine, as well as their metabolites. It also synthesizes some neurotransmitters and is involved in the regulation of amino acids, which are the building blocks of neurotransmitters and proteins. Supporting the function of neurotransmitters is essential for the overall operation of the body.


The liver maintains a steady balance of glucose and energy levels, which indirectly affects how neurotransmitters function within us. Imbalances in liver function can impact the levels of neurotransmitters and their activity in the nervous system. In short, the liver's involvement in managing the metabolism and detoxification of neurotransmitters, and keeping the body's overall metabolic balance highlights its sociable connection to our overall well-being and the health of our nervous system. Utilizing supplements like Osmosis Regenerate to support the liver and its purpose in our bodies is also a great way to support the brain and your well-being!


About 90% of the body's serotonin, which is known for regulating mood and happiness, is produced in the gut (GI tract). Other neurotransmitters such as GABA, dopamine, and norepinephrine are also produced in the gut. The gut and the brain are connected through the gut-brain axis, and the neurotransmitters produced within the gut can have a significant impact on mood, behavior, and overall brain function. This is one of the reasons why the gut is often referred to as the "second brain." Remember, you are what you eat.


Fun Fact:

Brain matter is roughly 60% fat and can shrink and expand due to lifestyle and certain diseases like cognitive impairment from Alzheimer's.


Things that hinder a healthy brain:

Alcohol

Drugs

Lack of exercise

Poor diet: not enough healthy fats, proteins, nutrients, etc.

Toxin build-up & continual exposure

Oxidative stress

Unmanaged emotions

Toxic environments (chemical & emotional)

Toxic liver


Note:

People with celiac disease (a severe immune reaction to gluten) often end up with brain shrinkage, gluten ataxia, which can result in brain damage. When our bodies don't absorb enough nutrients through the digestive tract it can lead to things such as this.


How to keep the brain healthy:

It's important to properly fuel the body for physical operation, growth, and overall function. Incorporating healthy foods is a key factor in keeping the brain and body healthy. Your brain and your gut are linked and fuel the system for operation. Neurotransmitters move on a line made of lipids which are essentially fats, making sure to include the appropriate type of fats in the body will help these synaptic transmissions occur and in some cases regenerate cognitive function. Exercising daily doesn't mean you need to do heavy lifting at the gym. An intermediate pilates class, yoga, walking, and HIIT workouts are all excellent ways to move your body and improve circulation and brain health. Muscle is the key to longevity, thank me later!


Take charge of your health and well-being! By starting a food log, being mindful of the things we put in our bodies, paying attention to when we don't feel our best, and analyzing why, we can start to fix this spiral. Purchasing local organic foods, food prep because we can make poor choices when we're tired and hungry, and implementing techniques that make you accountable and the goal attainable.


Incorporate things like:

  • Avocados

  • Bananas & Dark Berries

  • Dark Chocolate

  • Healthy Fats (i.e. Recovery)

  • Leafy Greens

  • Spinach

  • Pistachios & Pumpkin seeds

  • Lean meats like grass-fed & finished beef

  • Hemp protein as it contains all essential amino acids



Note:

Antibiotics are both friend & foe. They eliminate good and bad bacteria. They might make one symptom subside in turn causing multiple others to emerge.


Synergistic Connectivity:

The brain and liver are interconnected through various pathways in the human body. One of the key connections between the two is the hepatic portal system, which is responsible for transporting blood from the gastrointestinal tract (GI tract or gut), including the stomach and intestines, to the liver. This system ensures that nutrients and other substances absorbed from the digestive system are processed by the liver before entering general circulation. Remember that the liver plays a crucial role in metabolizing various substances, including medications, hormones, and toxins. It also contributes to the regulation of blood glucose levels and the synthesis of proteins essential for bodily functions.


While the liver is not typically considered a primary site for neurotransmitter production, it does play a role in the metabolism, and clearance of neurotransmitters, neuroactive substances, and their metabolites. Again, the liver is responsible for the detoxification of harmful substances, and the regulation of cholesterol levels in the body. Dysfunction in the liver can have systemic effects, potentially impacting brain function and overall health. For example, liver disease can lead to the buildup of toxins in the body, which may affect cognitive function and result in conditions such as hepatic encephalopathy (HE).


After neurotransmitters have served their purpose in transmitting signals, they are broken down and modified in the liver. For example, monoamine oxidase, an enzyme found in the liver, is involved in the breakdown of neurotransmitters such as dopamine, serotonin, and norepinephrine. Moreover, the brain also influences liver function through neural and hormonal pathways. For instance, the autonomic nervous system and the hypothalamic-pituitary-adrenal axis play roles in regulating liver function, metabolism, and the body's response to stress. The intricate connections between the brain and the liver highlight the importance of maintaining the health of both organs for overall well-being and proper bodily function.


Neurotransmitters Found In The Gut:

-Acetylcholine

-Dopamine

-GABA

-Histamine

-Melatonin

-Norepinephrine

-Serotonin


Introducing clean and healthy fats like Osmosis Recovery can significantly aid this process, enabling the body's function. Osmosis Regenerate & Recovery work synergistically to bolster various aspects of health and can even reverse certain types of illnesses, promoting a fuller and happier life. It's essential to ensure an adequate intake of amino acids, as without these vital nutrients, our bodies show signs of suffering that we often overlook.


Amino acids are the building blocks of proteins and play crucial roles in the human body. There are 20 different amino acids that are used to build proteins, and they can be categorized as either essential or nonessential. Essential amino acids cannot be synthesized by the body and must be obtained from the diet, while nonessential amino acids can be produced by the body itself. Once consumed, amino acids are used to build and repair tissues, such as muscle, skin, and organs. They are also involved in the production of enzymes, hormones, and neurotransmitters that are essential for various physiological processes. Amino acids are also vital for the transport and storage of nutrients and molecules throughout the body.

They also play a role in supporting the immune system and are involved in the synthesis of antibodies and other components of the immune response. Certain amino acids serve as precursors for other important molecules in the body; for example, the amino acid tryptophan is a precursor for serotonin, a neurotransmitter that regulates mood and sleep. In summary, amino acids are essential for numerous bodily functions, including tissue repair, hormone production, immune function, and neurotransmitter synthesis. Ensuring an adequate intake of protein-containing foods is important for providing the body with the necessary components to support overall health and well-being.


Note:

Once synthesized, neurotransmitters are packaged into vesicles in the presynaptic neuron and are released into the synaptic cleft in response to an action potential. They then bind to specific receptors on the postsynaptic neuron, initiating a response in the receiving neuron. After transmitting the signal, neurotransmitters are either broken down by enzymes, taken back up into the presynaptic neuron for recycling, or diffused away from the synapse.


When your liver is not functioning properly, it can manifest symptoms such as anxiety, dark spots on the hands and face, signs of premature aging, and irregular bowel movements, to name a few. The body relies on amino acids, which again are the building blocks of protein, and the amino acid Alpha-Ketoglutarate (AKG), a precursor to glutamate, which is a neurotransmitter, stimulates the protein synthesis process, helps to scavenge nitrogen, oxidizes nutrients, and provides energy to cell processes. Amino acids are important in the synthesis of neurotransmitters, and their availability in the body can influence the production and levels of neurotransmitters.


Now we know maintaining a healthy gut is important for overall well-being, including brain health. The gut and the brain are connected through the gut-brain axis, which allows communication between the central nervous system and the enteric nervous system of the gut. Research suggests that the balance of bacteria in the gut, known as the gut microbiota (microbiome), can influence brain function and behavior. Some studies have found that an unhealthy gut microbiota may be linked to conditions such as anxiety, depression, and even neurodegenerative diseases. Lastly, taking care of your gut health through a balanced diet, prebiotics, and other gut-friendly practices will have positive effects on brain function and mental-physical well-being.


Note:

Acetylcholine is a neurotransmitter that plays a role in memory, learning, attention, arousal, and involuntary muscle movement. By injecting botox (a botulinum toxin) you're shutting down the manufacturing of this neurotransmitter, thus weakening the muscle with repeated "treatments" in the name of beauty.


Ways to boost neurotransmitters naturally:

  • Adequate Protein Intake: Consuming foods rich in protein, which provides the necessary amino acids for neurotransmitter synthesis, can support the natural production of neurotransmitters.

    • Women need upwards of 120 grams of protein per day to support a thriving body. Our body's hormones fluctuate all day every day not just nearing your cycle

  • Balanced Diet: Eating a balanced diet that includes a variety of nutrient-dense foods, such as fruits, vegetables, whole grains, and healthy fats, can provide the essential nutrients required for neurotransmitter production and overall brain health.

    • Omega 3 fatty acids like those found in wild-caught fish

    • Omega 3, 6, 7, & 9 are found in Osmosis Recovery

  • Regular Exercise: Engaging in regular physical activity has been shown to enhance neurotransmitter function and promote the release of endorphins, which can positively impact mood and overall well-being.

    • Being active improves blood flow and circulation resulting in new cell production and overall body function

  • Stress Management: Practicing stress-reducing techniques such as deep breathing exercises, or yoga can help regulate the release of stress hormones and support healthy neurotransmitter balance.

    • Puzzles or brain activities help mental stimulation and can be therapeutic for some

    • Reading, coloring or sketching, or meditation are all great ways to relieve stress

    • Exercise is also an excellent way to relieve stress

  • Sunlight Exposure: Getting adequate sunlight exposure can help regulate serotonin levels, as sunlight triggers the production of this neurotransmitter in the brain.

    • Some Osmosis elixirs can help here, Sun Defense - Ageless Vitality - Emotional Well-Being

  • Adequate Sleep: Prioritizing good sleep hygiene and getting sufficient rest can support neurotransmitter balance, particularly in relation to mood-regulating neurotransmitters such as serotonin and dopamine.

    • Sleep can also be affected by liver damage or fatigue

    • Women need more sleep than men (8-12 hours)

  • Social Connections: Maintaining positive social connections and engaging in activities that bring joy and fulfillment can positively impact neurotransmitter activity.

    • 30 minutes of positive chat with a friend can help lift your mood significantly for the day

    • I would also consider meditation or prayer here as well



*Recovery contains macadamia nut oil


*Regenerate contains bioavailable vitamins and nutrients, product is not vegan


*Osmosis has not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease.

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